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Metabolic features of Cr GPDH expression in mammalian cells In addition to the decreased levels of DHAP and Gro3P when expressed in HeLa cells, Cr GPDH affected a few metabolites of central carbon metabolism ( Figure 3a-h )

Since PHH is not due to pancreatic -cell growth or hyperfunction but rather to changes in digestive anatomy and physiology induced by BS, partial or total pancreatectomy is not considered a therapeutic option