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The brain shrinks slightly when dehydrated, pulling away from the meninges and triggering pain signals

From a chemical perspective, Retatrutide consists of 39 amino acids and has a molecular weight of 4,731.33 g/mol

However, compared with HFD groups, the -diversity of the HFD + ABX groups was significantly reduced, confirming the clearance of gut microbiota under ABX treatment (Figure 4A)